Methodology

How RAGMD evaluates evidence

RAGMD is built for physicians who need to know which studies matter — not just whether an answer sounds plausible.

Step 1

Find broadly

RAGMD searches published literature relevant to the clinical question, starting with curated evidence objects and expanding when needed.

Step 2

Determine relevance

Studies are screened for population, intervention, comparator, and outcome fit — not just keyword overlap.

Step 3

Evaluate evidence

Design quality, directness, sample size, and methodological limitations inform how much each study should matter.

Step 4

Identify evidence drivers

Pivotal trials and landmark studies are surfaced explicitly so physicians can see what should drive the conclusion.

Step 5

Examine disagreement

Credible conflicting evidence is shown alongside supporting studies — not hidden behind a single narrative.

Step 6

Build confidence

Evidence Confidence summarizes strength, consistency, and completeness without fake precision.

Step 7

Preserve provenance

Claims remain linked to PubMed identifiers, study roles, and source excerpts you can inspect.

Sources, updates, and limitations

RAGMD prioritizes peer-reviewed literature with PubMed linkage. Maintained evidence questions are reviewed on a schedule and updated when materially new literature appears. Abstract-based synthesis is labeled when full text is unavailable.