Research · PMID 41808362

PubMed sourcedAbstract-based analysis

Relationship between menopausal hormone therapy and incidence risk of breast cancer: systematic review and meta-analysis.

Annals of medicine · December 2026 · Qing Wu, Liwen Shen, Shengtao Hu, Rui Yang, Yingnan Wang, et al.

What this study found

MHT is associated with a modest but significant increase in breast cancer risk, primarily driven by EPT. This risk was not observed with ET in observational studies, though trials suggested a protective effect.

systematic_review

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