Research · PMID 42430779
Reviewed by Neal Rouzier, MD, Preventive Medicine · Sep 2026
Testosterone therapy for female sexual dysfunction: a systematic review of the literature demonstrating outcomes in premenopausal and postmenopausal women.
The journal of sexual medicine · July 2026 · Vada A Furlan, Muhammed A M Hammad, Sophia Quesada, Sabrina Nguyen, Jessica Yih
What this study found
INTRODUCTION: Testosterone therapy is increasingly used for the treatment of female sexual dysfunction (FSD), particularly hypoactive sexual desire disorder (HSDD). While evidence and guidelines support its use in postmenopausal women, its role in premenopausal populations remains less clear.
How RAGMD uses this study
Clinical questions this paper informs
Synthesis lives on the evidence question — this page shows where the study sits in that analysis.
Primary study
Does testosterone therapy improve sexual function in postmenopausal women?
Testosterone therapy modestly improves sexual desire and related distress in selected postmenopausal women with hypoactive sexual desire disorder, particularly after oophorectomy. Monitoring for androgenic side effects and long-term safety is recommended.
Open evidence analysis