Estrogen, Breast Cancer & Safety

Cancer risk concerns, estrogen dominance debates, and evidence on HRT safety in women.

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Does hormone replacement therapy increase breast

Does hormone replacement therapy increase breast cancer risk?

Combined estrogen-progestin therapy is associated with a small increased breast cancer risk in WHI and observational data. Estrogen-alone in hysterectomized women showed lower risk in WHI, but interpretation depends on regimen, duration, and individual risk factors.

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