Topics / Menopause & Women's Health / Menopause, PMOS & PCOS
Subtopic
Menopause, PMOS & PCOS
Perimenopause, ovarian syndromes, and hormone patterns in women's health.
7 published deep analyses
Published deep analyses
Evidence in this subtopic
Should women with early surgical menopause
Should women with early surgical menopause receive hormone therapy?
Women with premature or early surgical menopause should generally receive hormone therapy until the average age of natural menopause unless contraindicated, to mitigate bone, cardiovascular, and symptom burden associated with early estrogen loss.
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Is fezolinetant effective for menopausal hot
Is fezolinetant effective for menopausal hot flashes?
Fezolinetant, a neurokinin-3 receptor antagonist, reduced moderate-to-severe vasomotor symptoms in randomized trials of postmenopausal women. It offers a non-hormonal option when estrogen is contraindicated or declined.
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What is the evidence for hormone
What is the evidence for hormone and metabolic therapy in PCOS?
PCOS management prioritizes lifestyle intervention, cycle regulation, and treatment of hyperandrogenism and metabolic risk. Metformin and hormonal contraceptives have evidence for specific endpoints; individualized plans depend on fertility goals.
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Does hormone therapy improve sleep disturbance
Does hormone therapy improve sleep disturbance in menopause?
Menopausal hormone therapy can improve sleep when vasomotor symptoms are a major driver of disruption. Benefits for primary insomnia without hot flashes are less consistent across trials.
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Does menopause cause weight gain and
Does menopause cause weight gain and can hormone therapy help?
Menopause is associated with central adiposity and lean mass loss independent of aging alone. Hormone therapy is not a weight-loss treatment but may attenuate some menopause-related body composition shifts in selected women.
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Does hormone therapy help depression or
Does hormone therapy help depression or anxiety during perimenopause?
Some trials suggest estrogen-based therapy may help depressive symptoms during the menopause transition, particularly when vasomotor symptoms coexist. It is not a substitute for standard treatment of major depressive disorder.
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Is menopause associated with cognitive changes
Is menopause associated with cognitive changes or brain fog?
Many women report subjective cognitive difficulty during perimenopause, often linked to sleep disruption and vasomotor symptoms. Objective cognitive testing shows subtle changes in some cohorts, but HRT is not established as a treatment for brain fog alone.
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